The metabolic engineering to increase HA molecular weight is the subject of a patent application (PCT filed August 2008). The High-HA technology has been developed through collaboration between the University of Queensland and the CRC Sugar Industry Innovation through Biotechnology.

 

 

 

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An unmet need exists for high molecular weight HA that can be produced from a safe, non-animal source at economical cost.

HA-based products generated over $2.25 billion in sales in the United States in 2006.

This included ophthalmic applications as well as visco-supplementation, visco-surgical aid, cosmetic injection, and anti-adhesive wound care applications.